Thermo Fisher Scientific Phospho-Talin 1 (Ser425) Polyclonal Antibody
Talin 1의 Ser425 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot에 적합하며, 인간 및 생쥐 시료에서 반응. PBS/glycerol 완충액에 보관되며, -20°C에서 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TLN1 (Accession Q9Y490), corresponding to amino acid residues around phosphorylated Ser425 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817610 |
Product Specific Information
This antibody detects endogenous levels of TALIN1 only when phosphorylated at Ser425.
Target Information
Talin is a multifunctional constituent of cell-substratum attachment sites and a high molecular weight protein (225–235 kDa) found in various tissues and cell types. It is localized at specific adherens junctions and cell-matrix associations characterized by filamentous actin at the cytoplasmic face. In cultured cells, talin is primarily found at adhesion plaques and fibrillar streaks underlying cell surface fibronectin. It interacts with vinculin and integrin, both localized at adhesion plaques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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