Thermo Fisher Scientific CCL21 Monoclonal Antibody (54111)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 1 publication 1 publication

ELISA (ELISA)

0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

54111

Immunogen

E. coli-derived recombinant human CCL21/6Ckine Ser24-Pro134 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCL21,uniProtId:O00585-1,ncbiNodeId:9606,antigenRange:24-134,antigenLength:134,antigenImageFileName:MA5-23751_CCL21_O00585-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23751_CCL21_O00585-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2610503

Product Specific Information

In Western blots, shows 100% cross-reactivity with recombinant human (rh) CCL24. Under reducing conditions, this antibody shows approximately 10-50% cross-reactivity with rhCCL2, 8, 13, 28, and rmCCL2. This antibody does not cross-react with rhCCL1, 3, 4, 5, 7, 9, 11, 14a, 15, 17, 18, 19, 20, 22, 23, 25, rmCCL1, 3, 4, 6, 7, 9, 11, 12, 19, 20, 21, 22, 24, 25, 28, or rrCCL20.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.