Thermo Fisher Scientific Phospho-Smad3 (Ser213) Polyclonal Antibody
Smad3 단백질의 Ser213 인산화 상태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합. 인간, 마우스, 랫트 반응성. 고순도 정제 및 안정적 PBS/glycerol 저장.
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Thermo Fisher Scientific Phospho-Smad3 (Ser213) Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMAD3 (Accession P84022), corresponding to amino acid residues around phosphorylated Ser213 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816415 |
Product Specific Information
This antibody detects endogenous levels of Smad3 only when phosphorylated at Serine 213.
Target Information
SMAD3 belongs to the SMAD family of proteins, which are similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma.
SMAD proteins act as signal transducers and transcriptional modulators mediating multiple signaling pathways.
SMAD3 functions as a transcriptional modulator activated by transforming growth factor-beta (TGF-β) and may play a role in carcinogenesis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-104942_SMAD3_P84022-1_Rabbit.svg, PA5-104942_SMAD3_P84022-1_Rabbit_PDP.jpeg)
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