Thermo Fisher Scientific EB1 Polyclonal Antibody
Human 및 Mouse에서 반응하는 Rabbit Polyclonal EB1 항체로, Western Blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 제품이며, TBS buffer(pH 7.0–8.0, 0.1% BSA) 포함. 미세소관 동역학과 세포 극성 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and 245 of human End-binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Chicken, and Orangutan
Target Information
EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes, regulating microtubule dynamics and organization.
The MAPRE genes encode EB1 family proteins, including MAPRE1 (EB1), MAPRE2 (RP1), and MAPRE3 (EBF3).
EB1 family members are ubiquitously expressed. The EB1 (MAPRE1) gene, located at 20q11.2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia.
EB1 interacts with the APC tumor-suppressor protein and plays critical roles in microtubule dynamics, cell polarity, and chromosome stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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