Thermo Fisher Scientific EB1 Polyclonal Antibody
Western blot과 Immunoprecipitation에 적합한 Rabbit Polyclonal 항체. 인간 EB1 단백질의 125–175번 잔기 영역을 면역원으로 제작. 비결합(Unconjugated) 형태의 액상 제품으로, 4°C에서 보관. 미세소관 결합 단백질 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 and 175 of human End-binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- The recommended shelf life for this product is 1 year from date of receipt.
Target Information
EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes, regulating the dynamics and organization of microtubules.
The MAPRE genes encode the EB1 family proteins: MAPRE1, MAPRE2, and MAPRE3, which code for EB1, RP1, and EBF3 proteins, respectively.
EB1 family members are ubiquitously expressed. The EB1 (MAPRE1) gene, located at 20q11.2, can be fused to MLL in adult pro-B acute lymphoblastic leukemia.
EB1 is a microtubule-associated protein that interacts with the APC tumor-suppressor protein, playing key roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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