Thermo Fisher Scientific ENG Monoclonal Antibody (OTI3D5), TrueMAB
ENG 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB 및 ICC/IF에 사용 가능. 인간 시료 반응성. Lyophilized 형태로 제공되며, 1 mg/mL 농도. 종양 혈관 및 증식성 내피세포 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D5 |
| Immunogen | Full length human recombinant protein of human ENG produced in HEK293T cell |
| Target Family | CD105 (Endoglin) |
| UniProt ID | P17813-1 |
| Antigen Range | 1–658 |
| Antigen Length | 658 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It forms an O- and N-glycosylated homodimer. Upregulation of Endoglin has been observed in tumor vasculature and proliferating endothelial cells, indicating its role as a proliferation-associated endothelial marker.
CD105 binds TGF-β1 and TGF-β3 with high affinity but not TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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