Thermo Fisher Scientific ATF1 Monoclonal Antibody (OTI7H3), TrueMAB
ATF1 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot과 IHC(파라핀 절편)에 적합합니다. 고순도의 Affinity chromatography 정제 항체이며 PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로 세포 내 ATF1 발현 및 인산화 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H3 |
| Immunogen | Full length human recombinant protein of human ATF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and the bZIP (basic-region leucine zipper) family. It regulates expression of downstream target genes related to growth, survival, and other cellular processes.
Phosphorylation at serine 63 by multiple kinases enhances its transcriptional activity and contributes to cell transformation.
Fusion of this gene with FUS (chromosome 16) or EWSR1 (chromosome 22) generates chimeric proteins observed in angiomatoid fibrous histiocytoma and clear cell sarcoma.
A pseudogene is located on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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