Thermo Fisher Scientific CD14 Monoclonal Antibody (MEM-15), Biotin
인간 및 비인간 영장류 CD14 항원을 인식하는 Mouse IgG1 단일클론 항체로, Biotin 결합 형식 제공. Flow Cytometry 및 Immunoprecipitation에 사용 가능하며, 4°C에서 보관. 단백질뇨 환자 유래 CD14 항원으로 면역화된 MEM-15 클론.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 2–5 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-15 |
| Immunogen | Human urinary proteins from the urine of a patient suffering from proteinuria |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071264 |
Additional Formats
Product Specific Information
This antibody reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils. It functions as a multifunctional lipopolysaccharide receptor and exists in both membrane-bound and soluble forms. Soluble CD14 (sCD14) can discriminate structural differences between lipopolysaccharides and contributes to neutralization of serum lipopolysaccharides. CD14 also binds apoptotic cells and influences allergic, inflammatory, and infectious processes. Alternative splicing produces multiple transcript variants encoding the same isoform. CD14 dysfunction is associated with mycobacterium chelonae infection and croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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