Thermo Fisher Scientific TRIP13 Polyclonal Antibody
TRIP13 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human, Mouse, Rat에 반응하며, 1 mg/mL 농도의 액상 형태. Affinity chromatography로 정제되었으며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TRIP13 (Accession Q15645), corresponding to amino acid residues F393–I432 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818201 |
Product Specific Information
Antibody detects endogenous levels of total TRIP13.
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with HPV16 E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with two different isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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