Thermo Fisher Scientific MEK1 N-Term Polyclonal Antibody, Biotin
Biotin으로 표지된 Thermo Fisher MEK1 N-Term Polyclonal Antibody로 인간, 생쥐, 랫트 반응성. WB 및 ELISA에 적합하며 MEK2와 교차 반응 없음. 장기 보관 시 -20°C에서 안정적이며 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
ELISA
- Tested Dilution: 1:40,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid residues near the N-terminus conjugated to KLH |
| Conjugate | Biotin |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 10 mg/mL BSA, 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot contents and freeze at -20°C or below.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This biotin-conjugated affinity purified antibody is directed against human MEK1 protein.
Cross-reactivity is expected with human, mouse, and rat based on sequence identity of the peptide immunogen.
This antibody does not react with the MEK2 isoform.
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation.
MAP2K1 is activated by various growth factors and cytokines, as well as by membrane-dependent depolarization and calcium influx.
MEK1 is activated by phosphorylation of serine 218 and 222 residues by Raf1.
It is involved in stress response signaling, apoptosis, and proliferative induction by cytokines.
Mutations in this gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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