Thermo Fisher Scientific CRYGD Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): Tested dilution 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MGKITLYEDR GFQGRHYECS SDHPNLQPYL SRCNSARVDS GCWMLYEQPN YSGLQYFLRR GDYADHQQWM GLSDSVRSCR LIPHSGSHRI RLYEREDYRG QMIEFTEDCS CLQDRFRFNE IHSLNVLEGS WVLYELSNYR GRQYLLMPGD YRRYQDWGAT NARVGSLRRV IDFS

Target Information

Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The ubiquitous class constitutes the major proteins of vertebrate eye lens, maintaining transparency and refractive index. Lens fiber cells lose nuclei during development, so crystallins are produced and retained throughout life, making them extremely stable proteins.
Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered a superfamily. Alpha and beta families are further divided into acidic and basic groups.
Gamma-crystallins are highly symmetrical, monomeric proteins lacking connecting peptides and terminal extensions. They are differentially regulated after early development.
Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized as a gene cluster. Aging or mutations in these genes are associated with cataract formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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