Thermo Fisher Scientific Phospho-cGKII (Ser126) Polyclonal Antibody
Phospho-cGKII (Ser126) 항체로 인간, 마우스, 랫트 시료에서 인산화된 cGKII 검출 가능. Western blot과 IHC(Paraffin)에 적합. Rabbit IgG 폴리클로날 형태이며 액상, 1 mg/mL 농도. 연구용 전용 제품으로 안정적인 PBS/glycerol 버퍼에 보관.
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- PA5105913
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Thermo Fisher Scientific Phospho-cGKII (Ser126) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRKG2 (Accession Q13237), corresponding to amino acid residues around phosphorylated Ser126 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817312 |
Product Specific Information
This antibody detects endogenous levels of cGKII only when phosphorylated at Ser126.
Target Information
PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity.
cGKII is thought to play a key role in various physiological pathways, including intestinal secretion of water and electrolytes induced by E. coli toxin STa and guanylin.
It is postulated to act as a molecular switch that couples cessation of proliferation and initiation of hypertrophic chondrocyte differentiation through attenuation of SOX9 function.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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