Thermo Fisher Scientific Phospho-PDGFRB (Tyr579, Tyr581) Polyclonal Antibody
PDGFRB 단백질의 Tyr579 및 Tyr581 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 검증됨. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDGFRB around the phosphorylation site of Tyr579/Tyr581 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817310 |
Target Information
PDGFRB is a receptor tyrosine kinase involved in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for cells of mesenchymal origin. The receptor’s ligand binding determines whether it forms homodimers or heterodimers with PDGF receptor alpha. The PDGFRB gene is located on chromosome 5, near genes for GM-CSF and M-CSF receptor, all potentially implicated in 5-q syndrome. A translocation between chromosomes 5 and 12 that fuses PDGFRB (CD140b) with ETV6 leads to chronic myeloproliferative disorder with eosinophilia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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