Thermo Fisher Scientific Nrf2 Recombinant Superclonal Antibody (21HCLC)
Nrf2 단백질을 인식하는 Recombinant Superclonal 항체로, 높은 특이성과 재현성을 제공합니다. Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 재조합 토끼 항체로 폴리클로날 감도와 모노클로날 일관성을 결합했습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 21HCLC |
| Immunogen | Recombinant protein corresponding to amino acids 352–605 of human Nrf2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532742 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitope sites on the target, providing higher detection sensitivity for low-abundance targets.
Each lot is produced with a known mixture of light and heavy chains, eliminating biological variability common in traditional polyclonal production.
Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
Nrf1 (also designated TCF11), Nrf2, and Nrf3 are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE (Maf recognition elements) sequences.
Nrf2 is widely expressed and translocates to the nucleus following exposure to xenobiotics and antioxidants, which stimulate its release from the repressor protein Keap1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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