Thermo Fisher Scientific PTPN3 Polyclonal Antibody
Rabbit polyclonal antibody against human PTPN3 for WB applications. Affinity-purified with >95% purity. Reacts with human, mouse, and rat. Supplied in liquid form, 1 mg/mL, stored at 4°C short term or -20°C long term. For research use only.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PTPN3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720658 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases. Coordinated control of kinases and phosphatases enables cells to switch rapidly between phosphorylated and dephosphorylated states in response to environmental stimuli. Dysregulation of these processes can lead to uncontrolled cell growth associated with cancers and developmental disorders. Regulation of phosphatase activity involves expression changes, localization, phosphorylation, and endogenous inhibitors. Since most phosphatases are not highly substrate-specific, alterations in their activity can broadly affect multiple signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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