Thermo Fisher Scientific PRRT2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PRRT2. Recombinant protein control fragment (Product #RP-91025). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRRT2,uniProtId:Q7Z6L0-1,ncbiNodeId:9606,antigenRange:152-268,antigenLength:340,antigenImageFileName:PA5-53168_PRRT2_Q7Z6L0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53168_PRRT2_Q7Z6L0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646014

Product Specific Information

Immunogen sequence: PKPALQPELP TQEDPTPEIL SESVGEKQEN GAVVPLQAGD GEEGPAPEPH SPPSKKSPPA NGAPPRVLQQ LVEEDRMRRA HSGHPGSPRG SLSRHPSSQL AGPGVEGGEG TQKPRDY

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.

Target Information

The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.