Thermo Fisher Scientific CD200R Monoclonal Antibody (OX108), PE

Applications

Flow Cytometry (Flow)

• Tested Dilution: Neat–1:10

Product Specifications

Product Specific Information

• Reconstitute with 1 mL of distilled water.
• After reconstitution, store undiluted at 4°C in the dark.
• For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
• Mouse anti-Human CD200R antibody, clone OX108, recognizes human CD200R (OX2R), a cell surface glycoprotein.

Target Information

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is restricted to myeloid lineage cells and may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed mainly by peripheral blood monocytes and neutrophils but also by T-lymphocytes and mast cells.
Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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