Thermo Fisher Scientific CDK9 Polyclonal Antibody
CDK9 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 액상 형태로 제공됩니다. 세포 성장 및 전사 조절 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human Cyclin-Dependent Kinase 9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
CDK9 is a serine/threonine kinase that forms an active holoenzyme complex with CyclinT1, playing a key role in regulating the eukaryotic cell cycle. It regulates cytokine-inducible transcription networks by facilitating promoter recognition of transcription factors and promotes RNA synthesis in genetic programs related to cell growth, differentiation, and viral pathogenesis. The CDK9/cyclin-K complex also phosphorylates the CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro. Chronic activation of CDK9 can lead to cardiac myocyte enlargement and predisposition to heart failure.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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