Thermo Fisher Scientific CD160 Monoclonal Antibody (BY55), PE, eBioscience

Thermo Fisher Scientific CD160 Monoclonal Antibody (BY55), PE, eBioscience

Applications

• Flow Cytometry (Flow)
  Tested Dilution: 5 µL (0.125 µg)/test
  View 3 publications

Product Specifications

Additional Formats

• Alexa Fluor 488
• eFluor 660
• Request custom conjugation

Product Specific Information

This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on:

• Natural killer (NK) cells
• Natural killer T (NKT) cells
• Activated and/or memory CD4 and CD8 T cells
• Gamma delta T cells
• Intraepithelial cells

CD160 binds herpes virus entry mediator (HVEM) in complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells, reducing proliferation and cytokine production.
Three alternative splice variants of CD160 have been identified in NK cells.

Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells.
Use at 5 µL (0.125 µg) per test in a final volume of 100 µL. Cell number may range from 10⁵ to 10⁸ cells/test.

Excitation: 488–561 nm
Emission: 578 nm
Laser Compatibility: Blue, Green, Yellow-Green
Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD160 is a receptor with broad specificity for classical and non-classical MHC class I molecules. It is expressed at the cell surface as a tightly disulfide-linked multimer and is involved in:

• Cell proliferation
• Cell surface receptor signaling pathways
• Cellular defense response
• Regulation of immune response

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지