Thermo Fisher Scientific CD160 Monoclonal Antibody (BY55), PE, eBioscience
인간 CD160 단백질을 인식하는 BY55 단클론 항체로, PE 형광 표지되어 있습니다. NK 및 T 세포 분석용으로 유세포 분석(Flow Cytometry)에 최적화되어 있으며, 사전 희석된 형태로 바로 사용 가능합니다. 4°C에서 암소 보관하며 동결 금지.
- 카탈로그번호
- 12-1609-42
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Thermo Fisher Scientific CD160 Monoclonal Antibody (BY55), PE, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.125 µg)/test
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BY55 |
| Conjugate | PE |
| Excitation/Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572583 |
Additional Formats
Product Specific Information
This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on:
- Natural killer (NK) cells
- Natural killer T (NKT) cells
- Activated and/or memory CD4 and CD8 T cells
- Gamma delta T cells
- Intraepithelial cells
CD160 binds herpes virus entry mediator (HVEM) in complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells, reducing proliferation and cytokine production.
Three alternative splice variants of CD160 have been identified in NK cells.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells.
Use at 5 µL (0.125 µg) per test in a final volume of 100 µL. Cell number may range from 10⁵ to 10⁸ cells/test.
Excitation: 488–561 nm
Emission: 578 nm
Laser Compatibility: Blue, Green, Yellow-Green
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD160 is a receptor with broad specificity for classical and non-classical MHC class I molecules. It is expressed at the cell surface as a tightly disulfide-linked multimer and is involved in:
- Cell proliferation
- Cell surface receptor signaling pathways
- Cellular defense response
- Regulation of immune response
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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