Thermo Fisher Scientific CARS Polyclonal Antibody
CARS 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품이며, PBS 기반 버퍼에 40% 글리세롤 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CARS. Recombinant protein control fragment (Product #RP-101867). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639295 |
Product Specific Information
Immunogen sequence:
SQCNLYMAAR KAVRKRPNQA LLENIALYLT HMLKIFGAVE EDSSLGFPVG GPGTSLSLEA TVMPYLQVLS EFREGVRKIA REQKVPEILQ LSDALRDNIL PELGVRFEDH EGLPTVVKLV DRNTLLKERE EKRRVE
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 86%
Target Information
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.
This gene is located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region are associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and various cancers including lung, ovarian, and breast cancer.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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