Thermo Fisher Scientific SLMAP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLMAP. Recombinant protein control fragment (Product #RP-102135). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLMAP,uniProtId:Q14BN4-1,ncbiNodeId:9606,antigenRange:624-773,antigenLength:828,antigenImageFileName:PA5-51708_SLMAP_Q14BN4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51708_SLMAP_Q14BN4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647594

Product Specific Information

Immunogen sequence: SEYEKEITSL QNSFQLRCQQ CEDQQREEAT RLQGELEKLR KEWNALETEC HSLKRENVLL SSELQRQEKE LHNSQKQSLE LTSDLSILQM SRKELENQVG SLKEQHLRDS ADLKTLLSKA ENQAKDVQKE YEKTQTVLSE LKLKFEMTEQ

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.

Target Information

Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.