Thermo Fisher Scientific Phospho-PKC zeta (Thr560) Recombinant Rabbit Monoclonal Antibody (ARC1617)
PKC zeta 단백질의 Thr560 인산화 부위를 특이적으로 인식하는 재조합 토끼 단일클론 항체입니다. Western blot과 ELISA에 적합하며, 높은 특이성과 재현성을 제공합니다. 인간 및 랫트 시료에 반응하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Phospho-PKC zeta (Thr560) Recombinant Rabbit Monoclonal Antibody (ARC1617)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1617 |
| Immunogen | A synthetic phosphorylated peptide around T560 of human PKC zeta (Q05513) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849792 |
Product Specific Information
Immunogen sequence: QLTPD
Target Information
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion, and membrane function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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