Thermo Fisher Scientific Phospho-Cdc37 (Ser13) Recombinant Rabbit Monoclonal Antibody (ARC1602)
Phospho-Cdc37 (Ser13) 항체로 인간, 생쥐, 랫트 시료에 반응하며 Western blot과 ELISA에 적합. HEK293 세포에서 발현된 재조합 단일클론 항체. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1602 |
| Immunogen | A synthetic phosphorylated peptide around S13 of human CDC37 (Q16543) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.09 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849788 |
Product Specific Information
- Immunogen sequence: EVSDD
Target Information
In S. cerevisiae, Cdc37 is an important regulator of the cell division cycle through its action on cyclin-dependent kinases (CDKs).
Cdc37 is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase.
HSP90 has been shown to interact with many of the same cellular targets as Cdc37. Cdc37 (also known as p50) forms complexes with Src-family kinases (Fyn, Yes, Fes, Lck, and Fgr), Raf, and pp60v-src.
Cdc37 functions as a chaperone both independently and together with HSP90, and is required for HSP90 binding to Cdk4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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