Thermo Fisher Scientific EDB-FN Chimeric Recombinant Human Monoclonal Antibody (G4)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

G4

Immunogen

2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EDB-FN,uniProtId:P02751-15,ncbiNodeId:9606,antigenRange:1-2477,antigenLength:2477,antigenImageFileName:MA5-48024_EDB-FN_P02751-15_Human.svg,antigenImageFileNamePDP:MA5-48024_EDB-FN_P02751-15_Human_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074467

Product Specific Information

Specificity: This antibody bind to human Extra-Domain containing fibronectin.

Target Information

EDB-FN is a variant of the fibronectin protein that contains an extra domain, known as the extra domain B. This extra domain is not present in the normal fibronectin protein and has been found to be expressed in certain tissues during embryonic development and in tumors. The extra domain has been implicated in cell adhesion, migration, and invasion, and has been shown to play a role in the progression and metastasis of certain cancers. Due to its unique expression pattern and functional properties, EDB-FN has been investigated as a potential target for cancer therapy and imaging.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.