Thermo Fisher Scientific EDB-FN Chimeric Recombinant Human Monoclonal Antibody (G4)
인간 EDB-FN 단백질을 인식하는 재조합 단일클론 항체로, Western blot, IHC, ELISA 등 다양한 분석에 적합합니다. HEK293 세포에서 발현된 IgG1 kappa 형식이며, Protein A로 정제되었습니다. 암 연구 및 세포 부착 관련 연구에 유용합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | G4 |
| Immunogen | 2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074467 |
Product Specific Information
Specificity: This antibody binds to human Extra-Domain containing fibronectin (EDB-FN).
Target Information
EDB-FN is a variant of the fibronectin protein that contains an extra domain, known as the extra domain B. This domain is not present in normal fibronectin and is expressed in certain tissues during embryonic development and in tumors.
It plays roles in cell adhesion, migration, and invasion, and is associated with cancer progression and metastasis.
Due to its unique expression and function, EDB-FN is studied as a potential target for cancer therapy and imaging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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