Thermo Fisher Scientific EDB-FN Chimeric Recombinant Human Monoclonal Antibody (A2)
인간 EDB-FN 단백질을 타깃으로 하는 재조합 인간 단클론 항체. Western blot, IHC(F), ELISA 등 다양한 분석에 사용 가능. HEK293 세포 발현, Protein A 정제, 1 mg/mL 농도의 액상 형태. 암 연구 및 세포 부착·이동 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | A2 |
| Immunogen | 2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074465 |
Product Specific Information
Specificity: This antibody binds to human Extra-Domain containing fibronectin (EDB-FN).
Target Information
EDB-FN is a variant of the fibronectin protein that includes an extra domain (extra domain B). This domain is absent in normal fibronectin but is expressed in certain tissues during embryonic development and in tumors. It plays roles in cell adhesion, migration, and invasion, contributing to cancer progression and metastasis. Due to its specific expression and function, EDB-FN is studied as a potential target for cancer therapy and imaging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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