Thermo Fisher Scientific CASP4 Monoclonal Antibody (OTI4A2), TrueMAB
인간 CASP4 단백질(aa 81-270)을 면역원으로 제작된 Mouse IgG1 단일클론 항체. Western blot에 적합하며, 동결건조 형태로 제공. PBS(pH 7.3, 8% 트레할로오스) 완충액에 보관하며, 재구성 후 1 mg/mL 농도 권장. 연구용 전용 제품.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 81–270 of human CASP4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family involved in the execution phase of apoptosis. Caspases are synthesized as inactive proenzymes requiring proteolytic processing to become active. CASP4 can self-activate and also activate caspase-1 precursor. Overexpression induces apoptosis, and alternative splicing produces distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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