Thermo Fisher Scientific MMP-28 Polyclonal Antibody
MMP-28 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 고농도(1 mg/mL) 액상 형태로 안정적 보관 가능. 연구용으로 조직 재생 및 신경 발달 연구에 활용.
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Thermo Fisher Scientific MMP-28 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human MMP28 (amino acids 201–300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein belonging to the peptidase M10A family. Matrix metalloproteinases are responsible for the breakdown of the extracellular matrix, essential for processes such as tissue remodeling, reproduction, and embryonic development.
Epilysin is produced by proliferating keratinocytes and mediates degradation of casein. Its expression increases upon skin injury, suggesting a role in tissue repair and homeostasis. It may also function in the nervous system, as incubation with rat embryonic brain tissue results in degradation of myelin proteins. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation, indicating a conserved role in neural development and modulation of the axonal-glial extracellular environment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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