Thermo Fisher Scientific DAXX Monoclonal Antibody (7A11)
Human DAXX 단백질을 검출하는 Mouse IgG1 단클론 항체로, WB, ICC/IF, Flow Cytometry, ELISA 등에 적합합니다. 비결합형 액상 형태이며 4°C 또는 -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific DAXX Monoclonal Antibody (7A11)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A11 |
| Immunogen | Purified recombinant fragment of human DAXX expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10987181 |
Product Specific Information
MA5-15552 targets DAXX in indirect ELISA, FACS, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human DAXX expressed in E. coli.
MA5-15552 detects DAXX, which has a predicted molecular weight of approximately 81 kDa.
Target Information
The DAXX gene encodes a multifunctional protein found in both the nucleus and cytoplasm. It interacts with various proteins, including apoptosis antigen Fas, centromere protein C, and transcription factor E26 oncogene homolog 1.
In the nucleus, DAXX acts as a transcription repressor binding to sumoylated transcription factors, and its repression can be relieved by sequestration into promyelocytic leukemia nuclear bodies or nucleoli.
In the cytoplasm, DAXX may regulate apoptosis. Its localization and function are modulated by post-translational modifications such as sumoylation, phosphorylation, and polyubiquitination.
Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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