Thermo Fisher Scientific Nkx2.5 Monoclonal Antibody (2E1)
NKX2.5 단백질을 표적하는 마우스 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 시료에 반응하며, 심장 형성과 발달 관련 연구에 유용합니다. 비결합형 액상 형태로 제공되며, 장기 보관 시 -20°C에서 저장 권장.
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Thermo Fisher Scientific Nkx2.5 Monoclonal Antibody (2E1)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- ELISA: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E1 |
| Immunogen | Purified recombinant fragment of human NKX2.5 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982077 |
Product Specific Information
MA5-15551 targets NKX2.5 in indirect ELISA and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human NKX2.5 expressed in E. coli.
MA5-15551 detects NKX2.5, which has a predicted molecular weight of approximately 35 kDa.
Target Information
The NKX2.5 gene encodes a homeobox-containing transcription factor involved in heart formation and development.
Mutations in this gene are associated with:
- Atrial septal defect with atrioventricular conduction defect
- Tetralogy of Fallot (heart malformation)
- Congenital hypothyroidism non-goitrous type 5 (non-autoimmune condition)
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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