Thermo Fisher Scientific CCR8 Polyclonal Antibody
Thermo Fisher Scientific의 CCR8 Polyclonal Antibody는 인간 CCR8 단백질을 인식하는 토끼 유래 IgG 항체입니다. IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 0.1% sodium azide 함유, 4°C 또는 -20°C 보관이 권장됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 28 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminal extracellular domain of human CCR8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550783 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla (100%)
Gibbon, Marmoset, Elephant, Panda (83%)
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven transmembrane G protein-coupled receptor. Chemokines and their receptors mediate migration of various cell types into inflammatory sites. CCR8 is preferentially expressed in the thymus. Known ligands include I-309, TARC, and MIP1 beta.
Studies suggest CCR8’s role in monocyte chemotaxis, thymic cell apoptosis, and positioning of activated T cells within antigenic challenge sites and lymphoid tissues.
CCR8 expression has been reported in spleen, thymus, NK cells, monocytes, T cells, and at lower levels in peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품의 항원 이미지 및 구조 관련 파일: PA5-33403_CCR8_P51685-1_Rabbit.svg, PA5-33403_CCR8_P51685-1_Rabbit_PDP.jpeg)
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