Thermo Fisher Scientific CCR6 Polyclonal Antibody
CCR6 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(Paraffin)에서 17 µg/mL 농도로 검증됨. 인간 및 영장류 간 높은 서열 동일성(최대 100%)을 보여줌. 액상 형태로 제공되며, 2–8°C에서 단기 보관 가능. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CCR6 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 17 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 2nd cytoplasmic domain of human CCR6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2550778 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon: 100%
- Monkey, Marmoset, Hamster: 83%
Target Information
CCR6 is a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors.
The gene is preferentially expressed by immature dendritic cells and memory T cells. Its ligand, macrophage inflammatory protein 3 alpha (MIP-3α), plays a key role in B-lineage maturation and antigen-driven B-cell differentiation. CCR6 may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses.
Alternatively spliced transcript variants encoding the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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