
Thermo Fisher Scientific CCR6 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
17 µg/mL
Product Specifications
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from 2nd cytoplasmic domain of human CCR6.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Wet ice
RRID
AB_2550778
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset, Hamster (83%).
Target Information
CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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