Thermo Fisher Scientific CCR7 Polyclonal Antibody
CCR7 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF 등 다양한 면역실험에 적합합니다. 인간 및 여러 종에 반응하며, 항원 친화 크로마토그래피로 정제된 고품질 액상 시약입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CCR7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 14 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 14 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Horse, Human, Non-human primate |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from C-terminus of human CCR7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550781 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Bat, Bovine, Horse (100%)
Mouse, Rat, Hamster, Elephant, Panda, Dog, Rabbit, Pig (94%)
Target Information
CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. It is induced by the Epstein Barr virus (EBV) and mediates EBV effects on B lymphocytes. CCR7 is expressed in blood, bone marrow, lymph node, and intestine, particularly in lymphoid tissues and activated B and T lymphocytes. It controls migration of memory T cells to inflamed tissues and stimulates dendritic cell maturation.
The chemokine ligand CCL19/ECL is a specific ligand for this receptor. CCR7 and other C-C chemokine receptors (CCR1–CCR5, Duffy antigen) are important for T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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