Thermo Fisher Scientific RAD54L2 Polyclonal Antibody
인간 RAD54L2 단백질을 인식하는 토끼 폴리클로날 항체. IHC, ICC/IF, ELISA 등에 사용 가능. 액상 형태로 제공되며, 0.1 mg/mL 농도. PBS 및 50% 글리세롤 버퍼에 보관, -20°C에서 냉동 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1178–1467 of human RAD54L2 (NP_0559212) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805484 |
Product Specific Information
Immunogen sequence:
ELQQYADVAA ARESRQSSPS TNAALPGPPA QLMDSSAVPG TALGTEPRLG GHCLNSSLLV TGQPCGDRHP VLDLRGHKRK LATPPAAQES SRRRSRKGHL PAPVQPYEHG YPVSGGFAMP PVSLNHNLTT PFTSQAGENS LFMGSTPSYY QLSNLLADAR LVFPVTTDPL VPAGPVSSSS TATSVTASNP SFMLNPSVPG ILPSYSLPFS QPLLSEPRMF APFPSPVLPS NLSRGMSIYP GYMSPHAGYP AGGLLRSQVP PFDSHEVAEV GFSSNDDEDK DDDVIEVTGK
Target Information
RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family. It contains a helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 functions as a DNA helicase regulating androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. It can be post-translationally sumoylated or phosphorylated upon DNA damage.
Adrenergic receptors (ARs), including a1, a2, b1, and b2 subtypes, are found in various tissues and differ in their responses to agonists and antagonists. ARs play a critical role in prostate cancer development, where transcriptional activity is partly regulated by coregulatory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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