Thermo Fisher Scientific IGF2BP1 Polyclonal Antibody
IGF2BP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, ICC/IF, ELISA, IP에 적합하며, Human, Mouse, Rat 시료에 반응. 고순도 Affinity 정제, PBS/glycerol buffer로 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 478–577 of human IGF2BP1/IMP1 (NP_006537.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805483 |
Product Specific Information
- Positive Samples: Jurkat, K-562, HepG2, HeLa, NIH/3T3, A-549, HL-60, Mouse liver
- Cellular Location: Cell projection, Cytoplasm, Nucleus, axon, dendrite, dendritic spine, filopodium, growth cone, lamellipodium, perinuclear region
Immunogen sequence:
NFFGPKEEVK LETHIRVPAS AAGRVIGKGG KTVNELQNLT AAEVVVPRDQ TPDENDQVIV KIIGHFYASQ MAQRKIRDIL AQVKQQHQKG QSNQAQARRK
Target Information
IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin, and beta-transducin repeat-containing protein, regulating their translation. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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