Thermo Fisher Scientific TET3 Monoclonal Antibody (OTI11E11), TrueMAB
TET3 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI11E11). Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS, 8% trehalose buffer에 보관하며, -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 241–568 of human TET3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TET3 is a methylcytosine dioxygenase belonging to the ten-eleven-translocation (TET) family. It catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is highly expressed in hematopoietic cells.
Unlike TET2, TET3 mutations have not been observed in myeloid malignancies. TET3 is implicated in DNA demethylation during early embryogenesis and may contribute to epigenetic reprogramming in zygotic and somatic cell nuclear reprogramming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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