Thermo Fisher Scientific KRT19 Monoclonal Antibody (OTI3D10), TrueMAB
Human KRT19 단백질(aa 240-390)을 항원으로 한 Mouse IgG2a 단클론 항체로, WB 및 IHC(P) 적용 가능. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose) 보존. 세포 분화 및 상피성 종양 진단 연구에 활용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D10 |
| Immunogen | Human recombinant protein fragment (aa 240–390 of human KRT19) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cytokeratin 19 is part of the intermediate filament protein family, showing biochemical diversity across human epithelial tissues with at least 20 polypeptides (40–68 kDa, pI 4.9–7.8).
Cytokeratin expression patterns are used to distinguish epithelial malignancies and assess epithelial differentiation.
Cytokeratin 19 is not expressed in hepatocytes, making it useful for identifying liver metastasis.
Cytokeratin antibodies aid in tumor differential diagnosis (IHC), cytopathology, and flow cytometry assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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