Thermo Fisher Scientific HLA-DR/DP/DQ Monoclonal Antibody (Bu26)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1:100–1:200

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Product Specifications

Additional Formats

• FITC
• Request custom conjugation

Product Specific Information

Mouse anti-Human HLA DP DQ DR antibody, clone Bu26 reacts with DP, DQ, and DR beta chains, which are expressed by antigen-presenting cells, B cells, monocytes, and activated T lymphocytes.

Target Information

MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen-presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells, and activated T lymphocytes.
Three loci—DR, DQ, and DP—encode the major expressed products of the human class II region.
Human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells, playing a critical role in initiating immune responses.

HLA and MHC antibodies are essential in Immunopeptidomics, aiding in the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.