Thermo Fisher Scientific HSP90AB1 (Heat Shock Protein 90) Monoclonal Antibody (HSP90AB1, 3952)
HSP90AB1 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체. Western blot 및 IHC에 적합하며, 인간 시료에 반응. 고순도 Protein A/G 정제, 보존제 없음, 연구용 전용.
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- 3326-MSM2-P1ABX
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Thermo Fisher Scientific HSP90AB1 (Heat Shock Protein 90) Monoclonal Antibody (HSP90AB1, 3952)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HSP90AB1, 3952 |
| Immunogen | Recombinant human HSP90AB1 protein fragment (around aa581–704) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat.
HSP90 is a 90 kDa protein that is induced under stress conditions and is one of the most abundant cellular proteins under non-stress conditions.
HSP90 proteins are highly conserved molecular chaperones involved in signal transduction, protein folding, degradation, and morphologic evolution.
They associate with cochaperones and play key roles in folding newly synthesized proteins or refolding denatured proteins after stress.
HSP90 interacts with several intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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