Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI1B4), TrueMAB
BTLA 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 적합하며, 인간 유래 시료에 반응. 동결건조 형태로 제공되며, 재구성 시 약 1 mg/mL 농도로 사용 가능. 면역세포 활성 조절 연구에 활용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Full length human recombinant protein of human BTLA produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor, modulating immune responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon T cell activation. It remains expressed on Th1 cells but not on Th2 cells. BTLA interacts with the tumor necrosis factor receptor family member HVEM, forming an important pathway for regulating lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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