Thermo Fisher Scientific KRT80 Polyclonal Antibody
Rabbit polyclonal antibody targeting human KRT80 for ICC/IF applications. Recognizes recombinant human KRT80 with high specificity. Supplied as liquid, unconjugated form, purified by antigen affinity chromatography. Suitable for research use only.
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Applications
- Immunocytochemistry (ICC/IF): Tested dilution 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human KRT80. Recombinant protein control fragment (Product #RP-105605) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663670 |
Product Specific Information
Immunogen sequence:
LGPSIPSPTTH HCCQPQDLDA ECLHRTELET KLKSLESFVE LMKTIYEQEL KDLAAQVKDV SVTVGMDSRC HIDLSGIVEE VKAQYDAV
Highest antigen sequence identity to the following orthologs:
- Mouse: 70%
- Rat: 71%
Target Information
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins.
The KRT80 gene encodes a type II epithelial keratin, structurally similar to type II hair keratin. This protein participates in cell differentiation, localizing near desmosomal plaques in early stages and dispersing throughout the cytoplasm in terminally differentiating cells.
Type II keratins are clustered in the chromosome region 12q13. Two transcript variants encoding distinct, fully functional isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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