Thermo Fisher Scientific Adenylate Cyclase 5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Adenylate Cyclase 5. Validated for ICC/IF at 0.25–2 µg/mL. Purified by antigen affinity chromatography and supplied in PBS with glycerol. Suitable for research use in GPCR signaling and cAMP pathway studies.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Adenylate Cyclase 5. Recombinant protein control fragment (Product #RP-108121). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662302 |
Product Specific Information
Immunogen sequence:
FTCNSRDLLGC LAQEHNISAS QVNACHVAES AVNYSLGDEQ GFCGSPWPNC NF
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 77%
Target Information
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium, and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
[provided by RefSeq, Dec 2010]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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