Thermo Fisher Scientific RND1 Polyclonal Antibody
Human RND1 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액에 포함되어 있습니다. 세포골격 재배열 연구에 활용 가능하며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific RND1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RND1. Recombinant protein control fragment (Product #RP-108124) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664280 |
Product Specific Information
Immunogen sequence:
TDLRTDLSTLM ELSHQKQAPI SYEQGCAIAK QLGAEIYLEG SAFTSEKSIH SI
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
RND1 lacks intrinsic GTPase activity and has a low affinity for GDP, constitutively binding GTP.
It controls rearrangements of the actin cytoskeleton and induces Rac-dependent neuritic process formation, partly by disrupting cortical actin filaments.
Causes formation of multiple neuritic processes from the cell body with disruption of cortical actin filaments.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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