Thermo Fisher Scientific HUNK Monoclonal Antibody (1C4)
HUNK 단백질을 표적으로 하는 Mouse IgG2a 단일클론 항체로 ELISA에 적합. 인간 반응성을 가지며 비결합형 액상 형태. -20°C 보관, 연구용으로만 사용. HUNK 관련 세포 신호전달 및 종양 연구에 활용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C4 |
| Immunogen | HUNK (NP_055401, 615–714 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:LHPTLVSFAH EDKNSPPKEE GLCCPPPVPS NGPMQPLGSP NCVKSRGRFP MMGIGQMLRK RHQSLQPSAD RPLEASLPPL QPLAPVNLAF DMADGVKTQC
Target Information
HUNK serine/threonine kinase (hormonally up-regulated Neu-associated kinase) is a member of the mitogen-activated protein kinase family, essential for mammary tumor metastasis.
HUNK deletion in mice did not alter viability, fertility, longevity, or tumor development and is dispensable for murine development.
HUNK participates in vesicular transport and regulates endocytosis via interaction with rabaptin-5 protein, inducing mammary gland changes during pregnancy.
Expression documented in mouse brain, breast, embryo, and fetus. ESTs isolated from several human tissue libraries, including normal ear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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