Thermo Fisher Scientific HUNK Monoclonal Antibody (2G3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

2G3

Immunogen

HUNK (NP_055401, 615 a.a. approximately 714 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HUNK,uniProtId:P57058-1,ncbiNodeId:9606,antigenRange:615-714,antigenLength:714,antigenImageFileName:H00030811-M03_HUNK_P57058-1_House_mouse.svg,antigenImageFileNamePDP:H00030811-M03_HUNK_P57058-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: LHPTLVSFAH EDKNSPPKEE GLCCPPPVPS NGPMQPLGSP NCVKSRGRFP MMGIGQMLRK RHQSLQPSAD RPLEASLPPL QPLAPVNLAF DMADGVKTQC

Target Information

HUNK serine/threonine kinase or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase family which is essential for mammary tumor metastasis. HUNK deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.