Thermo Fisher Scientific HUNK Monoclonal Antibody (2G3)
HUNK 단백질을 표적으로 하는 Mouse IgG2a 형 단클론 항체로 Western blot 및 ELISA에 적합. 인간 반응성, 액상 형태, PBS 버퍼에 보존제 무첨가. 연구용으로만 사용 가능하며 HUNK 관련 신호전달 및 종양 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G3 |
| Immunogen | HUNK (NP_055401, 615–714 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LHPTLVSFAH EDKNSPPKEE GLCCPPPVPS NGPMQPLGSP NCVKSRGRFP MMGIGQMLRK RHQSLQPSAD RPLEASLPPL QPLAPVNLAF DMADGVKTQC
Target Information
HUNK (hormonally up-regulated Neu-associated kinase) is a serine/threonine kinase belonging to the mitogen-activated protein kinase family, essential for mammary tumor metastasis.
HUNK deletion in mice did not alter viability, fertility, longevity, or tumor development, and is dispensable for murine development.
It participates in vesicular transport and regulates endocytosis through interaction with rabaptin-5 protein, inducing changes in mammary glands during pregnancy.
HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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