Thermo Fisher Scientific NRGN Monoclonal Antibody (OTI1A2), TrueMAB
Human NRGN 단백질(아미노산 1-78)을 인식하는 Mouse IgG1 단일클론 항체. Western Blot에 최적화되어 있으며, 무보존제 PBS 완충액에 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific NRGN Monoclonal Antibody (OTI1A2), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–78 of human NRGN produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. It encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium.
The NRGN gene consists of four exons and three introns; exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated sequences.
NRGN is suggested to be a direct target for thyroid hormone in the human brain, potentially explaining hypothyroidism-related mental effects during development and adulthood.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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