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Thermo Fisher Scientific alpha Actinin 1 Polyclonal Antibody
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Thermo Fisher Scientific alpha Actinin 1 Polyclonal Antibody

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Western blot 및 ICC/IF에 적합한 rabbit polyclonal 항체로, alpha Actinin 1 단백질을 인식합니다. 여러 종(인간, 마우스, 랫 등)에 반응하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, -20°C 보관.

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마지막 업데이트 2025. 08. 01. 오후 07:41
Thermo Fisher Scientific PA517308 alpha Actinin 1 Polyclonal Antibody 100 ul pk판매 단위 pk
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620,800원VAT 포함 682,880원

Thermo Fisher Scientific · Thermo Fisher Scientific alpha Actinin 1 Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution Publications
Western Blot (WB) 1:1,000 View 4 publications
Immunocytochemistry (ICC/IF) 1:25 View 5 publications

Product Specifications

항목 내용
Species Reactivity Hamster, Human, Mouse, Non-human primate, Rat
Published species Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide corresponding to carboxy-terminal residues of human alpha Actinin 1
Conjugate Unconjugated
Form Liquid
Concentration 5 µg/mL
Purification Affinity chromatography
Storage buffer 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol
Contains No preservative
Storage conditions -20°C
Shipping conditions Ambient (domestic); Wet ice (international)
RRID AB_10986146

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

Alpha Actinin 1 belongs to the spectrin gene superfamily, a group of cytoskeletal proteins including alpha and beta spectrins and dystrophins.
Alpha actinin is an actin-binding protein with multiple roles depending on the cell type.

  • In nonmuscle cells, it is found along microfilament bundles and adherens-type junctions, where it binds actin to the membrane.
  • In muscle cells (skeletal, cardiac, smooth), it localizes to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
    This gene encodes a nonmuscle, cytoskeletal alpha actinin isoform and maps to the same locus as the erythroid beta spectrin gene.
    Three transcript variants encoding different isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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