Thermo Fisher Scientific eIF4A1 Polyclonal Antibody
Western blot과 면역세포화학(ICC/IF)에 적합한 eIF4A1 폴리클로날 항체. Rabbit IgG 기반으로, Human, Mouse, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a sequence around Gly12 of human eIF4A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 88 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10978763 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
eIF4A2 is a 407-amino-acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, functions as a protein synthesis initiation factor, playing a key role in mRNA binding to the 43S pre-initiation ribosomal complex. It interacts with the NS5B protein of Hepatitis C virus (HCV), facilitating genomic RNA synthesis by unwinding secondary structures of the HCV genome. eIF4A2 is ubiquitously expressed in most normal tissues, with variable expression levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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