Thermo Fisher Scientific FBXO6 Monoclonal Antibody (OTI7A10), TrueMAB

Thermo Fisher Scientific FBXO6 Monoclonal Antibody (OTI7A10), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

The FBXO6 gene encodes a member of the F-box protein family, characterized by a ~40 amino acid F-box motif.
F-box proteins are one of the four subunits of the ubiquitin protein ligase complex SCFs (SKP1-cullin-F-box), which mediate phosphorylation-dependent ubiquitination.
They are categorized into three classes:

• Fbws: containing WD-40 domains
• Fbls: containing leucine-rich repeats
• Fbxs: containing diverse protein-protein interaction modules or no recognizable motifs

FBXO6 belongs to the Fbxs class, and its C-terminal region shows high similarity to rat NFB42 (neural F Box 42 kDa), potentially involved in cell cycle control.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.

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