Thermo Fisher Scientific FBXO25 Monoclonal Antibody (OTI6F11), TrueMAB
FBXO25 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI6F11). Western blot 및 IHC(P) 적용 가능. Human, Mouse, Rat 반응성. Lyophilized 형태로 공급되며, PBS buffer와 trehalose 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–191 of human FBXO25 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
FBXO25 belongs to the F-box protein family, characterized by a ~40 amino acid F-box motif.
F-box proteins are subunits of the SCF (SKP1-cullin-F-box) ubiquitin ligase complex, which mediates phosphorylation-dependent ubiquitination.
They are classified into three groups:
- Fbws: Contain WD-40 domains
- Fbls: Contain leucine-rich repeats
- Fbxs: Contain diverse protein–protein interaction modules or no recognizable motifs
FBXO25 is part of the Fbxs class.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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