Thermo Fisher Scientific L-Plastin Polyclonal Antibody
Human LCP1 특이성을 가진 Rabbit Polyclonal Antibody로, Western blot, ICC/IF, IP 등 다양한 응용에 적합합니다. 무보존제 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific L-Plastin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
| Immunoprecipitation (IP) | 5–10 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the center region of Human LCP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788051 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human LCP1.
Target Information
L-plastin is a leukocyte-specific actin bundling protein belonging to the fimbrin family. It contains two actin-binding domains and two EF-hand type calcium-binding domains. L-plastin is phosphorylated on a serine residue in its headpiece region in response to various inflammatory stimuli. It may play a role in regulating integrin-mediated adhesion in leukocytes.
L-plastin is expressed in most human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosterone in androgen receptor–positive prostate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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